棒狀桿菌 corynebacterium
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棒狀桿菌 Corynebacterium. Chun-Keung Yu DVM, PhD Department of Microbiology and Immunology. 棒狀桿菌. 革蘭氏陽性，不規則型桿菌 含異染顆粒，多位於一端 無運動性、無芽孢、無夾膜 染色抹片中，菌體常呈「人」字形或並排成柵狀。. Corynebacterium diphtheriae 白喉棒狀桿菌 Other corynebacteria (coryneform) 伺機感染病原. 致病性. 白喉棒狀桿菌存在病人或帶菌者的呼吸道、或皮膚傷口中，藉飛沫或接觸傳播。 - PowerPoint PPT PresentationTRANSCRIPT
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CorynebacteriumChun-Keung Yu DVM, PhDDepartment of Microbiology and Immunology
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Corynebacterium diphtheriae
Other corynebacteria (coryneform)
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(exotoxin)
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A-BABNAelongation factor EF-2
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5
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Clinical Diseases
Respiratory diphtheria Cutaneous diphtheria
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- Respiratory diphtheria2-6 ()
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LfflersPCR ()Elek
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Elek test ()
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Schick testIntradermal injection of diphtheria toxinNo skin reaction: have NT antibodyEdema + necrosis: no NT antibody, (patient is susceptible to diphtheria)
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(1) Penicillinerythromycin(2) DPT - diphtheria toxoid + pertussis + tetanus toxoid = DPT