© anzod registry australia 2002 - 2007 donors per million population aust 10 9 11 10 109 * nsw...

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© ANZOD Registry 0 10 20 30 40 2002 2003 2004 2005 2006 2007 0 10 20 30 40 QLD NSW * ACT * VIC TAS SA NT WA Australia 2002 - 2007 Donors Per Million Population Aust 10 9 11 10 10 9 * NSW population excludes residents of the NSW Southern Area Health Service * ACT population includes residents of the NSW Southern Area Health Service

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ANZOD Registry Australia 2002 - 2007 Donors Per Million Population Aust 10 9 11 10 109 * NSW population excludes residents of the NSW Southern Area Health Service * ACT population includes residents of the NSW Southern Area Health Service Slide 2 ANZOD Registry International Donor Statistics 2006 Donors PMP Source: IRODaT (International Registry of Organ Donation and Transplantation) Slide 3 ANZOD Registry Number of Deceased Donors Solid Organ Transplants and Patients on the Waiting List 2002 - 2007 Australia 2002 2003 2004 2005 2006 2007 Slide 4 ANZOD Registry Donor Gender States, Australia, New Zealand 1993-1997 1998-2002 2003-2007 QLD NSW ACT VIC TAS SA NT WA AUST NZ Slide 5 ANZOD Registry Age Group of Deceased Donors Australia 1999-2001 (545) 2002-2004 (603) 2005-2007 (604) Slide 6 ANZOD Registry Age and Gender Distribution of Donors Australia Males 1999-2001 (325) 2002-2004 (370) 2005-2007 (326) Slide 7 ANZOD Registry Age and Gender Distribution of Donors Australia Females 1999-2001 (220) 2002-2004 (233) 2005-2007 (278) Slide 8 ANZOD Registry Age Group of Deceased Donors New Zealand 1999-2001 (117) 2002-2004 (118) 2005-2007 (92) Slide 9 ANZOD Registry Age and Gender Distribution of Donors New Zealand Males 1999-2001 (59) 2002-2004 (65) 2005-2007 (46) Slide 10 ANZOD Registry Age and Gender Distribution of Donors New Zealand Females 1999-2001 (58) 2002-2004 (53) 2005-2007 (46) Slide 11 ANZOD Registry Cause of Donor Death Australia Slide 12 ANZOD Registry New Zealand Cause of Donor Death Slide 13 ANZOD Registry Mean Number of Recipients Per Donor Transplanted 1997 - 2007 Slide 14 ANZOD Registry Waiting List vs Deceased Donor Transplants Australia 2003 - 2007 Kidneys Waiting List * Tx Performed ** ** Includes kidneys sent from New Zealand * Source: NOMS (National Organ Matching System) Slide 15 ANZOD Registry Kidneys Waiting List * Tx Performed ** ** Not included kidneys sent to Australia: 2004 (1) 2005 (4) Waiting List vs Deceased Donor Transplants New Zealand 2003 - 2007 * Source of Waiting List NZ Donor Coordinators Slide 16 ANZOD Registry Total Donors 198 No request for kidney donation 6 Request for donation 192 No consent given 0 Consent given 192 Donors Kidneys not retrieved 26 Kidneys retrieved 358 Kidneys not transplanted 9 Kidneys Transplanted 349 (342 Recipients Transplanted) Kidneys en bloc 3 Double adult 4 AustraliaNew Zealand Outcome of Request for Kidney Donation 2007 Total Donors 38 No request for kidney donation 1 Request for donation 37 No consent given 0 Consent given 37 Donors Kidneys not retrieved 6 Kidneys retrieved 68 Kidneys not transplanted 3 Kidneys Transplanted 65 (65 Recipients Transplanted) Kidneys en bloc 0 Double adult 0 Slide 17 ANZOD Registry Donors (180)Kidney Recipients (342) Age of Donors Providing Transplanted Kidneys - Australia 2007 Slide 18 ANZOD Registry Donors (35)Kidney Recipients (65) Age of Donors Providing Transplanted Kidneys - New Zealand 2007 Slide 19 ANZOD Registry Deceased Donor Kidney Transplants by Transplant State 2006 2007 Australia and New Zealand Slide 20 ANZOD Registry Primary Deceased Patient and Graft Survival Australia 2001 - 2006 Kidney Slide 21 ANZOD Registry Primary Deceased Patient and Graft Survival New Zealand 2001 - 2006 Kidney Slide 22 ANZOD Registry Primary Deceased Kidney Graft Survival Terminal Serum Creatinine 2001 - 2006 Australia Serum Creatinine Slide 23 ANZOD Registry Waiting List vs Deceased Donor Transplants Australia 2003 - 2007 Liver Waiting List * Tx Performed ** x Slide 24 ANZOD Registry Waiting List vs Deceased Donor Transplants New Zealand 2003 - 2007 Liver Waiting List * Tx Performed ** Slide 25 ANZOD Registry Total Donors 198 No request for liver donation 10 Request for donation 188 No consent given 2 Consent given 186 Donors Livers not retrieved 46 Livers retrieved 140 Livers not transplanted 7 Livers Transplanted 133 * * 147 Recipients Transplanted 118 whole livers 28 split livers - 1 reduced size AustraliaNew Zealand Outcome of Request for Liver Donation 2007 Total Donors 38 No request for liver donation 0 Request for donation 38 No consent given 0 Consent given 38 Donors Livers not retrieved 6 Livers retrieved 32 Livers not transplanted 0 Livers Transplanted 32 * * 34 Recipients Transplanted 29 whole livers 4 split livers 1 reduced size Slide 26 ANZOD Registry Donors (133) Age of Donors Providing Transplanted Livers - Australia 2007 + Number of livers transplanted into two recipients (7) + (3) + (2) + (1) + Slide 27 ANZOD Registry Donors (32) Age of Donors Providing Transplanted Livers - New Zealand 2007 (1) + + Number of livers transplanted into two recipients (1) + Slide 28 ANZOD Registry Liver Transplants by Transplant State Australia and New Zealand 2006 - 2007 Slide 29 ANZOD Registry Deceased Patient and Graft Survival Australia 2002 - 2006 Liver Slide 30 ANZOD Registry Waiting List vs Deceased Transplants Australia 2003 - 2007 Heart Waiting List * Tx Performed ** ** Includes hearts sent from New Zealand Slide 31 ANZOD Registry Waiting List vs Deceased Transplants Australia 2003 - 2007 Waiting List * Tx Performed ** ** Includes lungs sent from New Zealand Heart/Lungs Double Lungs Single Lungs Slide 32 ANZOD Registry Waiting List vs Deceased Transplants New Zealand 2003 - 2007 Heart Waiting List * Tx Performed ** * Source of waiting list - NZ Donor Coordinators ** Not included hearts sent to Australia 2003 (3), 2004 (2), 2005 (3), 2006 (1), 2007 (3) Slide 33 ANZOD Registry Waiting List vs Deceased Transplants New Zealand 2003 - 2007 Waiting List * Tx Performed ** * Source of waiting list - NZ Donor Coordinators ** Not included number of lungs sent to Australia 2003 (9), 2004 (3), 2005 (3), 2006 (3), 2007 (4) Heart/Lungs Double Lungs Single Lungs Slide 34 ANZOD Registry Total Donors 198 No request for heart donation 37 Request for donation 161 No consent given 13 Consent given 148 Donors Hearts not retrieved 73 Hearts retrieved 75 Hearts not transplanted 13 Hearts Transplanted 62 Heart only - 56 Heart/Lungs - 6 AustraliaNew Zealand Outcome of Request for Heart Donation 2007 Total Donors 38 No request for heart donation 5 Request for donation 33 No consent given 0 Consent given 33 Donors Hearts not retrieved 21 Hearts retrieved 12 Hearts not transplanted 0 Hearts Transplanted 12 Heart only - 12 Heart/Lungs - 0 Slide 35 ANZOD Registry Donors (62) Age of Donors Providing Transplanted Hearts - Australia 2007 Slide 36 ANZOD Registry Donors (12) Age of Donors Providing Transplanted Hearts - New Zealand 2007 Slide 37 ANZOD Registry Heart Transplants by Transplant State Australia and New Zealand 2006 - 2007 Includes Hearts and Heart/Lungs Slide 38 ANZOD Registry Total Donors 198 No request for heart valves donation 98 Request for donation 100 No consent given 19 Consent given 81 Donors Hearts not retrieved 36 Hearts retrieved 45 Valves stored - 42 AustraliaNew Zealand Outcome of Request for Heart Valve Donation 2007 Total Donors 38 No request for heart valves donation 18 Request for donation 20 No consent given 4 Consent given 20 Donors Hearts not retrieved 6 Hearts retrieved 14 Valves stored - 14 Slide 39 ANZOD Registry Total Donors 198 No request for lung donation 40 Request for donation 158 No consent given 11 Consent given 147 Donors Lungs not retrieved 140 Lungs retrieved 154 Lungs not transplanted 4 Lungs Transplanted 150 ( Double lung - 65 recipients) (Heart/double lung - 6 recipients) (Single lung - 8 recipients) AustraliaNew Zealand Outcome of Request for Lung Donation 2007 Total Donors 38 No request for lung donation 6 Request for donation 32 No consent given 0 Consent given 32 Donors Lungs not retrieved 38 Lungs retrieved 26 Lungs not transplanted 0 Lungs Transplanted 26 ( Double lung - 13 recipients) (Heart/double lung - 0 recipients) (Single lung - 0 recipients) Slide 40 ANZOD Registry Donors (75) Age of Donors Providing Transplanted Lungs - Australia 2007 Slide 41 ANZOD Registry Donors (13) Age of Donors Providing Transplanted Lungs - New Zealand 2007 Slide 42 ANZOD Registry Lung Transplant Recipients 2006 - 2007 by Transplant State - Australia and NZ Slide 43 ANZOD Registry Bilateral Sequential (Double) and Single Lung Transplants by State 2006 - 2007 QLD NSW VIC WA Slide 44 ANZOD Registry Pancreas Waiting List ** Tx Performed Waiting List vs Deceased Transplants Australia 2003 - 2007 (7) * (5) * * Islets (8) * (6) * (7) * (3) * (6) * (1) * (4) * (7) * Slide 45 ANZOD Registry Total Donors 198 No request for pancreas donation 31 Request for donation 167 No consent given 9 Consent given 158 Donors Pancreas not retrieved 62 Pancreas retrieved 96 Pancreas not transplanted 63 Pancreas Transplanted 28 Islets Transplanted 5 (Kidney/Pancreas - 25) (Pancreas only - 3) AustraliaNew Zealand Outcome of Request for Pancreas Donation 2007 Total Donors 38 No request for pancreas donation 12 Request for donation 26 No consent given 0 Consent given 26 Donors Pancreas not retrieved 25 Pancreas retrieved 1 Pancreas not transplanted 0 Pancreas Transplanted 1 Islets Transplanted 0 ( Kidney/Pancreas - 1) (Pancreas only - 0) Slide 46 ANZOD Registry Donors (33) Pancreas Transplants (28) Islets Transplants (5) + Age of Donors Providing Transplanted Pancreas and Islets - Australia 2007 (1) + Slide 47 ANZOD Registry Pancreas Graft Survival According to Donor Age Groups 1987 - 2007 < 19 (n=112) > 40 (n =58) 20-39 (n=194) Slide 48 ANZOD Registry 20151050 Years Post Transplant 100 80 60 40 20 0 % Pancreas Graft Survival According to Cause of Donor Death 1987 - 2007 Cerebrovascular Disease (n=118) --------- Trauma (n=210) Slide 49 ANZOD Registry Acceptance of Pancreas for Transplantation and Research Australia 1998 - 2007 * Includes 23 Pancreas Islets transplanted from 2002-2007 Slide 50 ANZOD Registry Total Donors 38 No request for corneal donation 12 Request for donation 26 No consent given 5 Consent given 21 Donors Corneas not retrieved 2 Corneas retrieved 40 Corneas not suitable 0 Corneas Sent to Eye Bank 40 Total Donors 198 No request for corneal donation 36 Request for donation 162 No consent given 58 Consent given 104 Donors Corneas not retrieved 72 Corneas retrieved 136 Corneas not suitable 11 Corneas Sent to Eye Bank 125 AustraliaNew Zealand Outcome of Request for Corneal Donation 2007 Slide 51 ANZOD Registry Total Donors 198 No request for bone donation 105 Request for donation 93 No consent given 48 Consent given 45 Donors Bone not retrieved 34 Bone retrieved 11 Bone not transplanted 0 Bone Stored 11 AustraliaNew Zealand Outcome of Request for Bone Donation 2007 Total Donors 38 No request for bone donation 21 Request for donation 17 No consent given 1 Consent given 16 Donors Bone not retrieved 16 Bone retrieved 0 Bone not transplanted 0 Bone Stored 0