- . , ..., , . ..

: " : -, - , , -, , ; -, , "

, , , , ,

Acid-sensing ion channel (ASIC)

ASIC2

()

-2

Serum- and glucocorticoid-induced protein kinase (SGK) - ,

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) E3 -

, , , , ,

-1

Jacobus Henricus van't Hoff (1852 1911) The first Nobel Prize in Chemistry was awarded in 1901 toJacobus Henricus van 't Hoff, of theNetherlands, "for his discovery of the laws of chemical dynamics andosmotic pressurein solutions."

Organum vasculosum of lamina terminalis ,

Transient receptor potential channels (TRP channels)

TRPV1

(, ) , ,

, (, , ) (, , , ) , (, , , , )

--

() , ,

, , (, ) (, , -) , , (, )

,

Ernest Starling (1866-1927)STARLING EQUATION

(, , , . ( , , ; , ) (, , , .) ( , .) ( , , ) ( , )

: ( ) ( Na- ) ( -- , )

: , ( ) - ( )- ( -- , )

: ( ) ( ) ( ) ( , )

: - ( ) - ( ) - ( )

: ( )- ( )